Please find below details related to the forthcoming Academic Training Lecture series that will take place next week from Monday, 30 October to Friday, 3 November,online only:
By Ester Orlandi and Sandro Rossi, CNAO Foundation
Abstract
Radiotherapy is a mainstay of cancer treatment, using ionising radiation to damage the DNA of cancer cells. In most cases, a particle accelerator is used to generate a therapeutic beam. Conventional radiation therapy uses X-rays generated by a linac, andis widely available at relatively low cost. Hadrontherapy is a specific type of radiation therapy, which uses protons or other ions to provide a very conformal dose to the target volume in the treatment of many solid tumors. Nowadays it is often called particle therapy or heavy ion therapy. Hadrontherapy may also decrease the risk of adverse effects due to the reduced radiation dose to the normal tissues, especially for those tumors surrounded by radiosensitive organs.
This first lecture will recap the principles and rationale of hadron therapy, and provide an overview of the clinical results obtained so far.
Tuesday, 31 October at 11:00 - Robust treatment planning and plan verification strategies in scanning ion beam therapy -https://indico.cern.ch/event/1335920/
By Giuseppe Magro, CNAO Foundation
Abstract
One of the main objectives in radiotherapy is the conformal delivery of the prescribed dose to the tumour, meaning that cancer tissue should be irradiated whereas the surrounding healthy tissue should be spared as much as possible. Fully exploiting the advantages of ion therapy requires appropriate treatment planning, which takes into account the specificities of ion beams. This lecture will focus on the strategies for robust treatment planning and plan verification.
Radiobiology is a branch of science that studies the effects of ionizing radiation on biological tissues and their cellular and molecular components. It is a key field of research for the medical use of radiation for the treatment of cancer patients. This lecture focuses on the radiobiology of heavy ions used in hadron therapy, highlighting the opportunities and challenges for cancer treatment.
The unique properties of ion beams make them intrinsically suitable for highly conformal dose delivery to the tumour. However, the motion of organs situated in the thorax and abdomen strongly affects the precision of proton and carbon ion radiotherapy. The motion causes the displacement of the tumour, as well as modifications of the density along the therapeutical beam path in the body. This lecture covers state-of-the-art strategies for tumour motion monitoring and irradiation of moving targets.
Boron Neutron Capture Therapy (BNCT) is a technique that aims at selectively treating tumour cells while sparing healthy tissue, by concentrating a boron compound in the tumour mass andthen exposing the tumour to thermal neutrons. The technique was first proposed soon after the discovery of the neutron and the observation that boron easily captures low-energy neutrons. This lecture provides an overview of BNCT andof the plans to integrate it as an additional treatment option at the CNAO hadron therapy centre, complete with a discussion of the technical challenges.
HadroTherapy:
Dear Colleagues,Please find below details related to the forthcoming Academic Training Lecture series that will take place next week from Monday, 30 October to Friday, 3 November, online only:CERN Academic Training on hadron therapyMonday, 30 October at 11:00 - Introduction to hadrontherapy: rationale and clinical results - https://indico.cern.ch/event/1335919/By Ester Orlandi and Sandro Rossi, CNAO FoundationAbstractRadiotherapy is a mainstay of cancer treatment, using ionising radiation to damage the DNA of cancer cells. In most cases, a particle accelerator is used to generate a therapeutic beam. Conventional radiation therapy uses X-rays generated by a linac, and is widely available at relatively low cost. Hadrontherapy is a specific type of radiation therapy, which uses protons or other ions to provide a very conformal dose to the target volume in the treatment of many solid tumors. Nowadays it is often called particle therapy or heavy ion therapy. Hadrontherapy may also decrease the risk of adverse effects due to the reduced radiation dose to the normal tissues, especially for those tumors surrounded by radiosensitive organs.This first lecture will recap the principles and rationale of hadron therapy, and provide an overview of the clinical results obtained so far.Tuesday, 31 October at 11:00 - Robust treatment planning and plan verification strategies in scanning ion beam therapy -https://indico.cern.ch/event/1335920/By Giuseppe Magro, CNAO FoundationAbstractOne of the main objectives in radiotherapy is the conformal delivery of the prescribed dose to the tumour, meaning that cancer tissue should be irradiated whereas the surrounding healthy tissue should be spared as much as possible. Fully exploiting the advantages of ion therapy requires appropriate treatment planning, which takes into account the specificities of ion beams. This lecture will focus on the strategies for robust treatment planning and plan verification.Wednesday, 1 November at 11:00 - Heavy ions radiobiology: strengths and challenges for cancer treatment - https://indico.cern.ch/event/1335921/By Angelica Facoetti, CNAO FoundationAbstractRadiobiology is a branch of science that studies the effects of ionizing radiation on biological tissues and their cellular and molecular components. It is a key field of research for the medical use of radiation for the treatment of cancer patients. This lecture focuses on the radiobiology of heavy ions used in hadron therapy, highlighting the opportunities and challenges for cancer treatment.Thursday, 2 November at 11:00 - Motion management strategies in charged particle therapy - https://indico.cern.ch/event/1335922/By Andrea Pella, CNAO FoundationAbstractThe unique properties of ion beams make them intrinsically suitable for highly conformal dose delivery to the tumour. However, the motion of organs situated in the thorax and abdomen strongly affects the precision of proton and carbon ion radiotherapy. The motion causes the displacement of the tumour, as well as modifications of the density along the therapeutical beam path in the body. This lecture covers state-of-the-art strategies for tumour motion monitoring and irradiation of moving targets.Friday, 3 November at 11:00 - New treatment options at CNAO: the Boron Neutron Capture Therapy - https://indico.cern.ch/event/1335923/By Maria Monica Necchi, CNAO FoundationAbstractBoron Neutron Capture Therapy (BNCT) is a technique that aims at selectively treating tumour cells while sparing healthy tissue, by concentrating a boron compound in the tumour mass and then exposing the tumour to thermal neutrons. The technique was first proposed soon after the discovery of the neutron and the observation that boron easily captures low-energy neutrons. This lecture provides an overview of BNCT and of the plans to integrate it as an additional treatment option at the CNAO hadron therapy centre, complete with a discussion of the technical challenges.